The Mag-BIND® FFPE RNA 96 kit is specially designed for isolation of total RNA from formalin-fixed, paraffin-embedded tissue sections. The sample is first processed in special buffer by heating to deactivated RNases/DNase and deparaffinization. Then the lysate is treated with Proteinase K to digest proteins. The cleared lysate is then mixed with Mag-BIND® particles to capture the capture RNA. After few quick wash steps, purified RNA can be eluted with water or low salt buffer.