News
Rare Variant Allele Detection from Urinary cfDNA by Droplet Digital PCR
Extraction of cfDNA from 4 mL preserved urine sample.
An Automated, Turn-Key cfDNA Extraction Workflow Showcasing Low Frequency Variant Detection
Automated cell-free DNA extraction from 4 mL plasma.
UCL Genomics Core Facility
As a university core facility with an output of tens of thousands of samples per year, we work to meet the genomic needs of our collaborators for their research. We are unique in that we can work with
Omega Bio-tek Introduces Prefilled, Fully Automated cfDNA Extraction Kits
Omega Bio-tek, a leading manufacturer of Nucleic Acid purification kits, is thrilled to announce the launch of their latest product – Mag-Bind® cfDNA LSP Kit. This innovative kit is designed to provide researchers with a faster and more
Automated Plasmid Purifications using the MagBinder® Fit24: Mini, Midi, and More
Steven Cupello¹, Chris Stuart¹, Kiranmai Durvasula¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc., Norcross, GA 30071 MagBinder® Fit24 Nucleic Acid Purification System Figure 1. MagBinder® Fit24 Nucleic Acid Purification System The MagBinder® Fit24 is a new benchtop
Using ddPCR to Detect Rare Variant Alleles in cfDNA Samples on the MagBinder® Fit24 Platform
Carisa Townsend1, Kiranmai Durvasula1, Julie Baggs1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Recent advancements and studies have demonstrated the potential of cfDNA as a universal, non-invasive biomarker in cancer prognosis, diagnosis, and prenatal testing.
Automated DNA Purification Solution from 2 mL Whole Blood Using Omega Bio-tek’s Reagents on the MagBinder® Fit24 Platform
Carisa Townsend1, Kiranmai Durvasula1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction With advances in genomics research, personalized medicine, and sequencing-based technologies, there is a necessity for purification of high-quality genomic DNA from large volumes of
RNA Depletion in Plasmid DNA Extractions with Mag-Bind® TotalPure NGS
Introduction Traditionally, plasmid DNA purification hinges on alkaline lysis. In this method, bacteria, typically E. coli, containing the targeted plasmid DNA are harvested from overnight culture and resuspended in solution. A highly alkaline solution containing a detergent lyses
DNA from Saliva Performs Well Downstream, Despite Poor A260/A230 Ratios
The non-invasive nature of sample collection makes saliva an appealing sample type for patients and researchers alike. However, one hindrance to using saliva for genomic analysis is the appearance of low purity in eluates when quantified using absorbance
What are Biobanks?
In the era of precision medicine, biobanking has emerged as a crucial component in the realm of healthcare. A biobank is a specialized facility or repository that systematically collects, processes, stores, and manages biological samples and associated data
A Guide to Magnetic Bead-Based Nucleic Acid Extraction
Among the myriad techniques for nucleic acid extraction, magnetic beads stand out as an efficient and reliable tool to implement when automating extraction workflows. Magnetic bead-based extraction relies on the use of paramagnetic particles with coatings capable of
The Challenges of cfDNA Purification
Cell-free DNA (cfDNA) has emerged as a revolutionary tool in the realm of molecular diagnostics, offering a non-invasive window into the genetic information of various bodily tissues. As discussed in a previous post, the development of cfDNA technology