M1272

From Automated Plasmid Purification to In Vitro Transcription and mRNA Purification: Use Case for Early Discovery of mRNA-based Therapeutics

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Kiranmai Durvasula¹, Carisa Townsend¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Plasmids play a crucial role in the manufacturing and development of mRNA-based vaccines and therapeutics. As essential tools in molecular biology, plasmids serve as templates for in vitro transcription (IVT) processes, enabling the production of high-quality mRNA molecules for […]

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Automated Plasmid Midi Preps on a MagBinder® Fit24

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The Mag-Bind® Endo-free Plasmid Midi Kit (M1272) extracts high-yielding, high-quality plasmid DNA from a wide range of plasmid types and culture media:

  • High-yielding – Plasmid DNA yield up to 200 μg
  • Versatile – Process up to 50 mL bacterial culture with different plasmid types and culture medias
  • Transfection-quality – Endotoxin free plasmid DNA with endotoxins levels < 0.1 EU/µg
  • Pure – Contamination-free plasmid DNA with A260/A280 > 1.8 and A260/A230 > 1.8

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