Synthetic Biology & Biotechnology

From Automated Plasmid Purification to In Vitro Transcription and mRNA Purification: Use Case for Early Discovery of mRNA-based Therapeutics

Application Note / By

Kiranmai Durvasula¹, Carisa Townsend¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Plasmids play a crucial role in the manufacturing and development of mRNA-based vaccines and therapeutics. As essential tools in molecular biology, plasmids serve as templates for in vitro transcription (IVT) processes, enabling the production of high-quality mRNA molecules for […]

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High-Quality Plasmid DNA Purification in 9 Minutes Following Innovative FastFilter Technology

Poster / By

Introduction Traditional methods for isolating plasmid DNA often involve several centrifugation steps, making the process cumbersome and time consuming. Omega Bio-tek’s E.Z.N.A.® FastFilter Plasmid DNA Mini Kit is designed to purify high-quality plasmid DNA from up to 5 mL of culture in just 9 minutes. This Kit utilizes the first-of-its-kind FastFilter mini column nested within

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Reliable DNA Template Preparation Improves Cell-Free Protein Production from E. coli Plasmid Samples

Scientific Journal / By

A recent Synthetic Biology study from NIST demonstrates that DNA template preparation significantly impacts variability and protein yield in cell-free expression systems, highlighting extraction method as a critical factor in reproducibility. Using Omega Bio-tek’s Mag-Bind® plasmid purification kits, researchers showed that magnetic bead–based workflows help preserve DNA integrity and support more consistent, high-quality protein production.

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Simplifying Plasmid DNA Purification with Reliable RNA Removal

Scientific Journal / By

A study in Genes & Diseases demonstrates that Omega Bio-tek’s Mag-Bind® TotalPure NGS Kit can efficiently remove over 99% of contaminating RNA from plasmid DNA, significantly improving purity, integrity, and downstream performance compared to traditional methods. Leveraging this same magnetic bead technology, Omega Bio-tek delivers high-quality nucleic acid extraction solutions across plasmid, tissue, and environmental samples, enabling more reliable results in research and applied workflows.

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