Mag-Bind® FFPE DNA Kit

Price range: $0.00 through $1,756.90

Updates for 2026!

Isolate DNA from FFPE samples using magnetic beads

  • Safe Workflow -Xylene-free deparaffinization
  • Faster processing – Reduced incubation times for faster turnaround
  • Automation-Ready for High-Throughput – Compatible with leading open ended automation platforms (e.g., KingFisher™, Hamilton®)
  • Consistent and Reliable Performance – Supports NGS, qPCR, and other downstream workflows

NOTE: Same Buffer Sytem and protocol as the Mag-Bind FFPE DNA/RNA 96 kit’s “DNA only” protocol. Ideal for easy transition to co-purification of DNA and RNA from the same FFPE sample.

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Mag-Bind® FFPE DNA Kit

Ready-to-implement automated purification solution

All Mag-Bind® kits can be automated on most programmable robotic platforms, liquid handlers or magnetic processors. Learn more.

Off-the-shelf product doesn’t suit your needs? We’ll work with you to develop a customized product. Learn more.

Dedicated applications support will consult with you to develop and implement an automated solution that fits your specifications. Learn more.

Scripts available for all Mag-Bind® Kits for most open liquid handlers and common magnetic processors including the MagBinder® Fit24. Visit Automated Solutions for more information.

Mag-Bind® FFPE DNA 96 Kit is designed for the isolation of DNA from the same formalin-fixed, paraffin-embedded (FFPE) tissue sample. The protocol utilizes a specially formulated buffer system that not only partially reverses the formaldehyde-induced crosslinking but also ensures inhibitor-free purification of DNA. Magnetic bead-based extraction makes it suitable for both manual as well as automated processing on most open-ended liquid handling platforms as well as magnetic processors.


The Mag-Bind® FFPE DNA 96 Kit integrates a unique buffer system with the highly efficient binding properties of Mag-Bind® technology to isolate total DNA. The protocol utilizes non-toxic mineral oil in combination with heat for efficient deparaffinization of the FFPE sample eliminating the use of hazardous xylene.


Samples are first lysed in FDR Buffer aided by the presence of Proteinase K enzyme. The lysate is then heated to denature the proteinase and reverse the chemical crosslinking of the nucleic acids. Post-heating, the lysate is mixed with MB4 Buffer and Mag-Bind® Particles CH to bind DNA to the particles. Post several wash steps, DNA is eluted in Elution Buffer. Purified DNA is suitable for a variety of downstream applications including PCR, qPCR, next generation sequencing, and more.

For Research Use Only. Not for use in diagnostic procedures.

FEATURESSPECIFICATIONS
Starting Amount3-8 paraffin sample sections between 5-10 μm
Starting MaterialFFPE tissue
Elution Volume30-50 µL
TechnologyMagnetic beads
Processing ModeAutomated, Manual
Throughput96

High-Quality DNA Extracted from Different FFPE Sample Types

Figure 1. Average DNA yield and quality from different FFPE samples. Genomic DNA was isolated from 3x10 µm FFPE sections (n=3) using Omega Bio-tek’s Mag-Bind® FFPE DNA 96 Kit, following manufacturer’s recommended protocol. Purified DNA was quantified using Thermo Scientific’s NanoDrop™ 2000c system.

Downstream-Ready Purification with Minimal Carryover Contamination

Figure 2. Average Ct values obtained on 10X and 100X dilutions of DNA purified from 3x10 µm sections of different FFPE samples (n=3). The extraction resulted in amplifiable DNA at both dilutions tested, indicating successful purification using the Mag-Bind® FFPE DNA 96 Kit without severe carryover contamination.

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