Overcoming the Challenges of Extraction Nucleic Acids from FFPE Samples
Formalin-fixed, paraffin-embedded (FFPE) samples are invaluable resources for molecular pathology and biomedical research, preserving tissue architecture and enabling long-term storage. However, the very fixation process that protects these samples often complicates the extraction of high-quality nucleic acids, especially
Webinar: Maximize Efficiency: Dual DNA and RNA Purification Solution from the Same Sample
Extraction of DNA and RNA from the sample source maximizes the information gained from precious or limited materials, providing an integrated molecular view. It enables researchers to correlate both genomic and transcriptomic data from the cellular matrix, eliminating
Sequencing of Repeat Expansions in Molecular Diagnostics: Comparing Hybridization-based and CRISPR-Cas9-based Approaches
Medicover Genetics conducted a comparison of hybridization and CRISPR-Cas9-based sequencing enrichment methods, utilizing the Mag-Bind® Blood & Tissue DNA HDQ 96 Kit for DNA extraction.
Webinar:
June 17th 10:00 am EST
Unlocking Urinary cfDNA Insights: A Complete Workflow from Sample Collection to Detection
Circulating free DNA (cfDNA) derived from urine has emerged as a promising biomarker in the field of non-invasive diagnostics, particularly in oncology, nephrology, and other areas of medical research. With advances in next-generation sequencing (NGS) and other molecular
Rare Variant Allele Detection from Urinary cfDNA by Droplet Digital PCR
Extraction of cfDNA from 4 mL preserved urine sample.
An Automated, Turn-Key cfDNA Extraction Workflow Showcasing Low Frequency Variant Detection
Automated cell-free DNA extraction from 4 mL plasma.
UCL Genomics Core Facility
As a university core facility with an output of tens of thousands of samples per year, we work to meet the genomic needs of our collaborators for their research. We are unique in that we can work with
Automated Plasmid Purifications using the MagBinder® Fit24: Mini, Midi, and More
Steven Cupello¹, Chris Stuart¹, Kiranmai Durvasula¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc., Norcross, GA 30071 MagBinder® Fit24 Nucleic Acid Purification System Figure 1. MagBinder® Fit24 Nucleic Acid Purification System The MagBinder® Fit24 is a new benchtop
Using ddPCR to Detect Rare Variant Alleles in cfDNA Samples on the MagBinder® Fit24 Platform
Carisa Townsend1, Kiranmai Durvasula1, Julie Baggs1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Recent advancements and studies have demonstrated the potential of cfDNA as a universal, non-invasive biomarker in cancer prognosis, diagnosis, and prenatal testing.
Automated DNA Purification Solution from 2 mL Whole Blood Using Omega Bio-tek’s Reagents on the MagBinder® Fit24 Platform
Carisa Townsend1, Kiranmai Durvasula1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction With advances in genomics research, personalized medicine, and sequencing-based technologies, there is a necessity for purification of high-quality genomic DNA from large volumes of
RNA Depletion in Plasmid DNA Extractions with Mag-Bind® TotalPure NGS
Introduction Traditionally, plasmid DNA purification hinges on alkaline lysis. In this method, bacteria, typically E. coli, containing the targeted plasmid DNA are harvested from overnight culture and resuspended in solution. A highly alkaline solution containing a detergent lyses