Monitoring SARS-CoV-2 in Wastewater Samples Using High-Quality RNA Clean-Up for Whole-Genome Sequencing
A recent PLOS ONE study demonstrates how optimized whole-genome sequencing of SARS-CoV-2 in wastewater can provide highly sensitive, population-level surveillance—even detecting variants in low-signal samples. By incorporating Mag-Bind® TotalPure NGS for RNA clean-up and library purification, researchers significantly improved genome coverage, sequencing depth, and overall data quality from challenging environmental samples.