Clean-up

From Automated Plasmid Purification to In Vitro Transcription and mRNA Purification: Use Case for Early Discovery of mRNA-based Therapeutics

Application Note / By

Kiranmai Durvasula¹, Carisa Townsend¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Plasmids play a crucial role in the manufacturing and development of mRNA-based vaccines and therapeutics. As essential tools in molecular biology, plasmids serve as templates for in vitro transcription (IVT) processes, enabling the production of high-quality mRNA molecules for […]

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Automated DNA Cleanup for NGS Workflow

Poster / By

Interested in Automating your NGS Cleanup? Tell us about your project! Automation Support Form Country * United StatesAfghanistanAland IslandsAlbaniaAlgeriaAmerican SamoaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBoliviaBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBruneiBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCook IslandsCosta RicaCôte d'IvoireCroatiaCubaCuracaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEast TimorEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuamGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard

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Monitoring SARS-CoV-2 in Wastewater Samples Using High-Quality RNA Clean-Up for Whole-Genome Sequencing

Scientific Journal / By

A recent PLOS ONE study demonstrates how optimized whole-genome sequencing of SARS-CoV-2 in wastewater can provide highly sensitive, population-level surveillance—even detecting variants in low-signal samples. By incorporating Mag-Bind® TotalPure NGS for RNA clean-up and library purification, researchers significantly improved genome coverage, sequencing depth, and overall data quality from challenging environmental samples.

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Enabling Cost-Effective Next-Generation Sequencing with Reliable Nucleic Acid Clean-Up

Scientific Journal / By

A recent study demonstrates that Omega Bio-tek’s Mag-Bind® TotalPure NGS Beads deliver high-quality DNA clean-up and size selection for 16S microbiome library preparation, matching the performance of leading alternatives. By offering comparable sequencing results at a significantly lower cost, Omega Bio-tek enables more accessible and scalable next-generation sequencing workflows for metagenomics research.

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Optimizing Environmental DNA Extraction from Turbid and Clear Water Samples for Reliable Fish Biodiversity Detection

Scientific Journal / By

This study shows that effective eDNA workflows must be adapted for both high-turbidity estuarine samples and low-turbidity offshore waters, where DNA yield and variability differ significantly. The Omega Bio-tek E.Z.N.A.® Tissue DNA Kit, paired with inhibitor removal, delivered consistent performance in complex, high-turbidity samples, while the E.Z.N.A.® Water DNA Kit demonstrated strong performance in higher-DNA environments but should be used cautiously in low-concentration, clear-water conditions.

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