Precision Medicine

Performance Evaluation of Automated cfDNA Extraction Using the MagBinder® Fit24 for Fetal RhD Genotyping Using the FetoGnost® Kit RHD

Claudia Pitzl¹, Christina Holzinger¹, Kiranmai Durvasula², Julie Baggs², and Travis Butts² ¹ingenetix GmbH, Vienna, Austria ²Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Cell-free DNA (cfDNA) isolated from maternal plasma is widely used in non-invasive prenatal testing (NIPT) such as Fetal Rhesus Factor D (RhD) genotyping which determines whether an RhD incompatibility exists between mother and […]

Performance Evaluation of Automated cfDNA Extraction Using the MagBinder® Fit24 for Fetal RhD Genotyping Using the FetoGnost® Kit RHD Read More »

Evaluation and Comparison of Yield, Quality, and Next Generation Sequencing Metrics of DNA and RNA Extracted from the Same FFPE Sample Using Three Commercially Available Kits

Danny Flanigan¹, Lauren Golan¹, Archie Li¹, Kiranmai Durvasula¹, Chris Stuart¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Formalin-fixed paraffin-embedded (FFPE) tissue samples are invaluable biospecimens that are increasingly being used in molecular level analyses and gene expression studies aiding the fields of cancer genomics, pathological diagnosis, biomarker discovery, immunotherapy research,

Evaluation and Comparison of Yield, Quality, and Next Generation Sequencing Metrics of DNA and RNA Extracted from the Same FFPE Sample Using Three Commercially Available Kits Read More »

Advancing Methylation Analysis with Reliable DNA Extraction

A recent study in Clinical Epigenetics (Nuttall et al., 2025) shows that enzymatic methylation sequencing delivers higher-quality, more reliable results than traditional methods across challenging clinical samples. Powered by high-purity DNA extraction from Omega Bio-tek’s Mag-Bind® kits, the workflow enabled advanced whole-genome methylation insights and revealed new biomarkers linked to treatment response in leukemia.

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Plasma cfDNA Methylation Profiling for Lung Cancer Detection Using Targeted EM-seq

This Scientific Reports study demonstrates how integrating cfDNA methylation patterns with fragment size analysis enables highly sensitive, non-invasive detection of lung cancer from plasma samples. By providing high-quality cfDNA isolation for targeted EM-seq workflows, Omega Bio-tek’s Mag-Bind® cfDNA Kit supports the precision and reliability required for advanced liquid biopsy diagnostics.

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cfDNA Extraction Simplified: An Automated Workflow on Omega Bio-tek’s Cutting-Edge Platform

Brandon Easparro¹, Claire McClain¹, Sara Amirahmadi¹, Tesfaye Kemsi¹, Jeff Roeder¹, and Travis Butts¹ Omega Bio-tek, Inc., Norcross, GA 30071 As presented at SLAS 2024 Abstract Plasma is a well-known sample type used in the isolation of cell-free DNA (cfDNA) for disease detection, diagnosis, and monitoring. cfDNA consists of small fragments of DNA released by cells

cfDNA Extraction Simplified: An Automated Workflow on Omega Bio-tek’s Cutting-Edge Platform Read More »

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