RNA

Evaluation and Comparison of Yield, Quality, and Next Generation Sequencing Metrics of DNA and RNA Extracted from the Same FFPE Sample Using Three Commercially Available Kits

Application Note / By

Danny Flanigan¹, Lauren Golan¹, Archie Li¹, Kiranmai Durvasula¹, Chris Stuart¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Formalin-fixed paraffin-embedded (FFPE) tissue samples are invaluable biospecimens that are increasingly being used in molecular level analyses and gene expression studies aiding the fields of cancer genomics, pathological diagnosis, biomarker discovery, immunotherapy research,

Evaluation and Comparison of Yield, Quality, and Next Generation Sequencing Metrics of DNA and RNA Extracted from the Same FFPE Sample Using Three Commercially Available Kits Read More »

Monitoring SARS-CoV-2 in Wastewater Samples Using High-Quality RNA Clean-Up for Whole-Genome Sequencing

Scientific Journal / By

A recent PLOS ONE study demonstrates how optimized whole-genome sequencing of SARS-CoV-2 in wastewater can provide highly sensitive, population-level surveillance—even detecting variants in low-signal samples. By incorporating Mag-Bind® TotalPure NGS for RNA clean-up and library purification, researchers significantly improved genome coverage, sequencing depth, and overall data quality from challenging environmental samples.

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