Biobanking

Key Applications of Nucleic Acid Purification in BioBanking

A biobank is a collection of biospecimens directly linked to one’s personal health information that are held for medical research purposes.

Blood Banks

  • Collection of blood for research, emergency medicine, etc.
  • Collects, separates, tests, and stores blood until need for use.
  • Stored blood can be separated into red blood cells, platelets, cryoprecipiate, and plasma for uses specific to the component.

Implications of Nucleic Acid Purification in BioBanking

  • Analysis of DNA sequence can be used to create disease treatments based on biomarkers present within the genetic profile.
  • Population Studies
  • Extracting cfDNA can be especially tricky because cfDNA exists in relatively low concentrations within the plasma.
  • This makes extracting enough cfDNA to be useful for downstream applications like PCR and sequencing difficult.
  • Omega Bio-tek’s products can extract high yielding, high-quality nucleic acids that are suitable for biobanking, even if they occur in low concentrations.

Resources:

Schneikart, G., Tavarini, S., Sammicheli, C., Torricelli, G., Guidotti, S., Andreano, E., … & Bardelli, M. (2020). The respiratory syncytial virus fusion protein-specific B cell receptor repertoire reshaped by post-fusion subunit vaccination. Vaccine38(50), 7916-7927.

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