Precision Medicine
Key Applications of Nucleic Acid Purification in Precision Medicine
Biomarker discovery:
- Researchers analyze purified nucleic acids to identify molecular markers that can help identify disease stage, treatment response, and other patient outcomes.
NGS:
- High quality nucleic acid purification is crucial for NGS. Genome analysis achieved with NGS can help identify genetic variations in tumors, like mutations.
Companion Diagnostics:
- Isolating a patient’s DNA can be used to predict if a patient will benefit from a targeted therapy.
Implications of Nucleic Acid Purification in Precision Medicine
- High quality nucleic acid purification is beneficial to precision medicine in a myriad of ways.
- Early disease detection:
- Sampling methods like liquid biopsy can allow clinicians to detect a disease like cancer at its earliest stages.
- Targeted therapies:
- Identifying and analyzing genetic markers allows researchers to develop treatments that can be precisely targeted to a patient’s ailment.
- Omega Bio-tek’s products are able to extract high yielding and high-quality nucleic acids from a wide range of samples that are free of inhibitors, ensuring their success in these downstream applications.
Omega Bio-tek Products for Precision Medicine Applications
Plasma and Serum (cfDNA):
Formalin Fixed Tissue (FFPE):
Blood and Tissue:
Clean-up:
Resources:
Kim, J. Y., An, S., Kwak, N., Kim, D., & Yim, J. J. (2023). Distinct Microbiome Signature Predicts Early Treatment Response of Patients With Mycobacterium Abscessus Pulmonary Disease. In B98. THE HAPPY COUPLE: BRONCHIECTASIS AND NONTUBERCULOUS MYCOBACTERIA (pp. A4243-A4243). American Thoracic Society.
