MB Fit24™ cfDNA Kit


Pre-scripted solution for the purification of cfDNA from up to 4 mL plasma samples

Features and Benefits

  • Ease-of-use – Automation-ready cartridges pre-filled with reagents
  • Convenience – No reagent preparation and buffer dispensing
  • High-quality purification – Up to 4mL samples lysed offline eluted in as little as 50 μL

Learn more about the MagBinder® Fit24

SKU#: B3298-10-48PF (48 Cartridges for use with the MagBinder® Fit24)

CE-IVD Kits coming soon!

Unlock the power of precision with the MB Fit24™ cfDNA Kit, your go-to solution for fast, dependable isolation of circulating DNA. Designed for use with the MagBinder® Fit24 Nucleic Acid Purification System, this kit revolutionizes your workflow, allowing for the extraction of circulating DNA from up to 4 mL plasma/serum samples.

Automation-Ready Efficiency

Experience the simplicity of the MB Fit24™ cfDNA Kit. This kit is automation-ready, featuring reagent cartridges pre-filled with industry-leading Mag-Bind® reagents along with validated scripts for the MagBinder® Fit24 instrument. Enjoy fast and consistent results, with a semi-automated extraction workflow capable of processing up to 24 x 4mL samples in less than 55 minutes.

Enhanced Ease-of-use

Say goodbye to time-consuming steps. The MB Fit24™ cfDNA Kit streamlines your process by eliminating reagent preparation and buffer dispensing. Samples are lysed offline, and the lysate is transferred to the reagent well containing the binding buffer. This unique binding buffer allows for the processing of large sample volumes, up to 4 mL, in a semi-automated format without the need for sample splitting.

Reproducible, High-Quality Output

Benefit from the enhanced properties of Mag-Bind® Particles CH magnetic beads, ensuring fast and efficient separation during steps involving large volumes. The high-binding capacity reduces the volume of magnetic particles required, resulting in a decreased elution volume. Obtain DNA from up to 4 mL plasma or serum eluted in as little as 50 μL, with the kit optimized to extract smaller DNA fragments (150-400 bp) while minimizing the binding of larger fragments.

Transform your DNA extraction experience with the MB Fit24™ cfDNA Kit. Elevate efficiency, accuracy, and convenience in your laboratory. Contact your Omega Bio-tek representative to embark on a journey of seamless cfDNA isolation.

Starting amount 
Up to 4 mL plasma/serum 
Elution Volume 
50-100 uL 
Magnetic Beads 
Processing Mode 
Estimated offline Processing 
40 minutes 
Online Processing Time 
53 minutes 
Downstream applications: NGS, qPCR 

TapeStation Analysis Shows Well-Defined cfDNA Peaks

Figure 1. TapeStation Analysis of cfDNA extracted from 4 mL of plasma from Lot L show well-defined cfDNA peaks, with additional multimers above.

Average Ct Values Illustrate Absence of Inhibitors

Figure 2. qPCR analysis results in a ΔCt within the expected range of 1-1.5 for the cfDNA extracted using the MB Fit24 cfDNA Kit, illustrating reduced inhibition.

Product Information

Protocol ManualProduct ManualEnglish
MagBinder® Fit24 – Automated, high-volume DNA & RNA purification BrochureProduct LiteratureEnglish
cfDNA Extraction Simplified: An Automated Workflow on Omega Bio-tek’s MagBinder Fit24 PlatformApplication NoteEnglish
Using ddPCR to Detect Rare Variant Alleles in cfDNA Samples on the MagBinder Fit24 PlatformApplication NoteEnglish

Safety Data Sheets

ComponentsHazard StandardsLanguagesLinkhf:tax:dlp_document_languagehf:tax:dlp_document_hazard-standard
DS BufferGHSEnglishenglishghs
DS BufferGHSSpanishspanishghs
DS BufferREACHEnglishenglishreach
DS BufferREACHDanishdanishreach
DS BufferREACHFinnishfinnishreach
DS BufferREACHFrenchfrenchreach
DS BufferREACHGermangermanreach
DS BufferREACHItalianitalianreach
DS BufferREACHNorwegiannorwegianreach
DS BufferREACHSpanishspanishreach
DS BufferREACHSwedishswedishreach
DS BufferWHMSEnglishenglishwhms
DS BufferWHMSFrenchfrenchwhms
DS BufferREACHDutchdutchreach
DS BufferREACHHungarianhungarianreach
DS BufferREACHPortugueseportuguesereach
Elution BufferGHSEnglishenglishghs
Elution BufferGHSSpanishspanishghs
Elution BufferREACHEnglishenglishreach
Elution BufferREACHDanishdanishreach
Elution BufferREACHFinnishfinnishreach
Elution BufferREACHFrenchfrenchreach
Elution BufferREACHGermangermanreach
Elution BufferREACHItalianitalianreach
Elution BufferREACHNorwegiannorwegianreach
Elution BufferREACHSpanishspanishreach
Elution BufferREACHSwedishswedishreach
Elution BufferWHMSEnglishenglishwhms
Elution BufferWHMSFrenchfrenchwhms
Elution BufferREACHDutchdutchreach
Elution BufferREACHHungarianhungarianreach
Elution BufferREACHPortugueseportuguesereach
GT7 Buffer v1.1REACHDanishdanishreach
GT7 Buffer v1.1REACHDutchdutchreach
GT7 Buffer v1.1REACHEnglishenglishreach
GT7 Buffer v1.1REACHFrenchfrenchreach
GT7 Buffer v1.1REACHGermangermanreach
GT7 Buffer v1.1REACHHungarianhungarianreach
GT7 Buffer v1.1REACHItalianitalianreach
GT7 Buffer v1.1REACHNorwegiannorwegianreach
GT7 Buffer v1.1REACHPortugueseportuguesereach
GT7 Buffer v1.1REACHSpanishspanishreach
GT7 Buffer v1.1REACHSwedishswedishreach
GT7 Buffer v1.1GHSEnglishenglishghs
GT7 Buffer v1.1GHSSpanishspanishghs
GT7 Buffer v1.1REACHFinnishfinnishreach
GT7 Buffer v1.1WHMSEnglishenglishwhms
GT7 Buffer v1.1WHMSFrenchfrenchwhms
JSB BufferGHSEnglishenglishghs
JSB BufferGHSSpanishspanishghs
JSB BufferREACHEnglishenglishreach
JSB BufferREACHDanishdanishreach
JSB BufferREACHFinnishfinnishreach
JSB BufferREACHFrenchfrenchreach
JSB BufferREACHGermangermanreach
JSB BufferREACHItalianitalianreach
JSB BufferREACHNorwegiannorwegianreach
JSB BufferREACHSpanishspanishreach
JSB BufferREACHSwedishswedishreach
JSB BufferWHMSEnglishenglishwhms
JSB BufferWHMSFrenchfrenchwhms
JSB BufferREACHDutchdutchreach
JSB BufferREACHHungarianhungarianreach
JSB BufferREACHPortugueseportuguesereach
Mag-Bind Particles CHGHSEnglishenglishghs
Mag-Bind Particles CHGHSSpanishspanishghs
Mag-Bind Particles CHREACHEnglishenglishreach
Mag-Bind Particles CHREACHDanishdanishreach
Mag-Bind Particles CHREACHFinnishfinnishreach
Mag-Bind Particles CHREACHFrenchfrenchreach
Mag-Bind Particles CHREACHGermangermanreach
Mag-Bind Particles CHREACHItalianitalianreach
Mag-Bind Particles CHREACHNorwegiannorwegianreach
Mag-Bind Particles CHREACHSpanishspanishreach
Mag-Bind Particles CHREACHSwedishswedishreach
Mag-Bind Particles CHWHMSEnglishenglishwhms
Mag-Bind Particles CHWHMSFrenchfrenchwhms
Mag-Bind Particles CHREACHDutchdutchreach
Mag-Bind Particles CHREACHHungarianhungarianreach
Mag-Bind Particles CHREACHPortugueseportuguesereach
Proteinase K SolutionGHSEnglishenglishghs
Proteinase K SolutionGHSSpanishspanishghs
Proteinase K SolutionREACHEnglishenglishreach
Proteinase K SolutionREACHDanishdanishreach
Proteinase K SolutionREACHFinnishfinnishreach
Proteinase K SolutionREACHFrenchfrenchreach
Proteinase K SolutionREACHGermangermanreach
Proteinase K SolutionREACHItalianitalianreach
Proteinase K SolutionREACHNorwegiannorwegianreach
Proteinase K SolutionREACHSpanishspanishreach
Proteinase K SolutionREACHSwedishswedishreach
Proteinase K SolutionWHMSEnglishenglishwhms
Proteinase K SolutionWHMSFrenchfrenchwhms
Proteinase K SolutionREACHDutchdutchreach
Proteinase K SolutionREACHHungarianhungarianreach
Proteinase K SolutionREACHPortugueseportuguesereach
eSPW BufferGHSEnglishenglishghs
eSPW BufferREACHEnglishenglishreach
eSPW BufferWHMSEnglishenglishwhms
eSPW BufferWHMSFrenchfrenchwhms
eSPW BufferREACHDanishdanishreach
eSPW BufferREACHDutchdutchreach
eSPW BufferREACHFinnishfinnishreach
eSPW BufferREACHFrenchfrenchreach
eSPW BufferREACHGermangermanreach
eSPW BufferREACHHungarianhungarianreach
eSPW BufferREACHItalianitalianreach
eSPW BufferREACHNorwegiannorwegianreach
eSPW BufferREACHPortugueseportuguesereach
eSPW BufferREACHSpanishspanishreach
eSPW BufferREACHSwedishswedishreach
eSPW BufferGHSSpanishspanishghs
DS BufferREACHGreekgreekreach
Elution BufferREACHGreekgreekreach
eSPW BufferREACHGreekgreekreach
GT7 Buffer v1.1REACHGreekgreekreach
JSB BufferREACHGreekgreekreach
Mag-Bind Particles CHREACHGreekgreekreach
Proteinase K SolutionREACHGreekgreekreach
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