Extraction of DNA and RNA from the sample source maximizes the information gained from precious or limited materials, providing an integrated molecular view. It enables researchers to correlate both genomic and transcriptomic data from the cellular matrix, eliminating the problem of sample variability. Omega Bio-tek has developed an innovative nucleic acid extraction methodology (Mag-Bind® DNA/RNA […]
Medicover Genetics conducted a comparison of hybridization and CRISPR-Cas9-based sequencing enrichment methods, utilizing the Mag-Bind® Blood & Tissue DNA HDQ 96 Kit for DNA extraction.
Extraction of cfDNA from 4 mL preserved urine sample.
Rare Variant Allele Detection from Urinary cfDNA by Droplet Digital PCR Read More »
Automated cell-free DNA extraction from 4 mL plasma.
Steven Cupello¹, Chris Stuart¹, Kiranmai Durvasula¹, Julie Baggs¹, and Travis Butts¹ ¹Omega Bio-tek, Inc., Norcross, GA 30071 MagBinder® Fit24 Nucleic Acid Purification System Figure 1. MagBinder® Fit24 Nucleic Acid Purification System The MagBinder® Fit24 is a new benchtop nucleic acid purification system designed to meet the needs of low-to-moderate throughput users by providing semi-automated purification
Automated Plasmid Purifications using the MagBinder® Fit24: Mini, Midi, and More Read More »
Carisa Townsend1, Kiranmai Durvasula1, Julie Baggs1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Recent advancements and studies have demonstrated the potential of cfDNA as a universal, non-invasive biomarker in cancer prognosis, diagnosis, and prenatal testing. cfDNA are found in low abundance and in a background of contaminating genomic DNA making it a
Carisa Townsend1, Kiranmai Durvasula1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction With advances in genomics research, personalized medicine, and sequencing-based technologies, there is a necessity for purification of high-quality genomic DNA from large volumes of blood. The rapidly growing landscape of biorepositories that store large amounts of DNA from an enormous number
Introduction Traditionally, plasmid DNA purification hinges on alkaline lysis. In this method, bacteria, typically E. coli, containing the targeted plasmid DNA are harvested from overnight culture and resuspended in solution. A highly alkaline solution containing a detergent lyses the bacteria cells and denatures both the plasmid and genomic DNA. The addition of a highly acidic
RNA Depletion in Plasmid DNA Extractions with Mag-Bind® TotalPure NGS Read More »
The non-invasive nature of sample collection makes saliva an appealing sample type for patients and researchers alike. However, one hindrance to using saliva for genomic analysis is the appearance of low purity in eluates when quantified using absorbance ratios. Here, we discuss the nature of absorbance ratios and contextualize their meaning when analyzing extractions from
DNA from Saliva Performs Well Downstream, Despite Poor A260/A230 Ratios Read More »
In the era of precision medicine, biobanking has emerged as a crucial component in the realm of healthcare. A biobank is a specialized facility or repository that systematically collects, processes, stores, and manages biological samples and associated data for use in research and medical studies. The primary purpose of a biobank is to provide a
What are Biobanks? Read More »
