Oncology

Webinar:
June 17th 10:00 am EST
Unlocking Urinary cfDNA Insights: A Complete Workflow from Sample Collection to Detection

Circulating free DNA (cfDNA) derived from urine has emerged as a promising biomarker in the field of non-invasive diagnostics, particularly in oncology, nephrology, and other areas of medical research. With advances in next-generation sequencing (NGS) and other molecular techniques, such as droplet digital PCR (ddPCR), the analysis of cfDNA from urine holds the potential to […]

Webinar:
June 17th 10:00 am EST
Unlocking Urinary cfDNA Insights: A Complete Workflow from Sample Collection to Detection
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Using ddPCR to Detect Rare Variant Alleles in cfDNA Samples on the MagBinder® Fit24 Platform

Carisa Townsend1, Kiranmai Durvasula1, Julie Baggs1, and Travis Butts1 Omega Bio-tek, Inc, Norcross, GA 30071 Introduction Recent advancements and studies have demonstrated the potential of cfDNA as a universal, non-invasive biomarker in cancer prognosis, diagnosis, and prenatal testing. cfDNA are found in low abundance and in a background of contaminating genomic DNA making it a

Using ddPCR to Detect Rare Variant Alleles in cfDNA Samples on the MagBinder® Fit24 Platform Read More »

The Challenges of cfDNA Purification

Cell-free DNA (cfDNA) has emerged as a revolutionary tool in the realm of molecular diagnostics, offering a non-invasive window into the genetic information of various bodily tissues. As discussed in a previous post, the development of cfDNA technology is a large step forward in detecting and profiling circulating biomarkers to derive clinically relevant information. However,

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What is NGS?

Next-Generation Sequencing (NGS) is a cutting-edge technology used to sequence nucleotides in a DNA or RNA molecule. Unlike Sanger Sequencing, which can sequence only one DNA fragment at a time, NGS allows researchers to sequence multiple DNA fragments in parallel in a single run. This high-throughput approach revolutionizes our ability to decode complex genomes efficiently

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Liquid vs. Solid Biopsy

Revolutionary advancements in medical technologies have armed physicians with state-of-the-art methods for detecting and monitoring cancer.  Two of these methods are liquid and solid biopsies which provide physicians and researchers with integral information about a patient’s condition.  What is a Solid Biopsy? Solid biopsies are the traditional method of analyzing tumors; this typically involves extracting samples of tissue from the tumor using a needle or

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Mag-Bind® FFPE DNA Kit: The Ultimate Solution for Genomic DNA Purification from Formalin-Fixed Paraffin-Embedded Tissue Samples

Formalin-fixed paraffin-embedded (FFPE) tissue samples are commonly used for preserving and storing biological samples, such as cancer tumor samples, for future analysis. However, the formalin fixation and paraffin embedding process can significantly impact the quality and yield of extracted DNA, making it challenging for downstream applications such as PCR and NGS. Omega Bio-tek developed the Mag-Bind® FFPE

Mag-Bind® FFPE DNA Kit: The Ultimate Solution for Genomic DNA Purification from Formalin-Fixed Paraffin-Embedded Tissue Samples Read More »

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