Product Application

RNA Depletion in Plasmid DNA Extractions with Mag-Bind® TotalPure NGS

Clean Up, Downstream Applications, Product Application / By

Introduction Traditionally, plasmid DNA purification hinges on alkaline lysis. In this method, bacteria, typically E. coli, containing the targeted plasmid DNA are harvested from overnight culture and resuspended in solution. A highly alkaline solution containing a detergent lyses the bacteria cells and denatures both the plasmid and genomic DNA. The addition of a highly acidic […]

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DNA from Saliva Performs Well Downstream, Despite Poor A260/A230 Ratios

Downstream Applications, Product Application / By

The non-invasive nature of sample collection makes saliva an appealing sample type for patients and researchers alike. However, one hindrance to using saliva for genomic analysis is the appearance of low purity in eluates when quantified using absorbance ratios. Here, we discuss the nature of absorbance ratios and contextualize their meaning when analyzing extractions from

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DNA Sequencing Could Help Restore Genomic Diversity to at-risk Populations of Pumas in California

Leave a Comment / Environmental, Product Application / By

Introduction The consequences of the expansion of human development have been especially felt in California where human activity has eradicated several apex predators, like the California Grizzly and gray wolf. Unlike these predators, the puma, also called the mountain lion or cougar, has continued to populate the state, though their population is threatened by the continued

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What is PCR?

Leave a Comment / Biobanking, Pathogen Detection, Precision Medicine, Product Application / By

Polymerase Chain Reaction (PCR) is a molecular biology technique used to amplify and replicate specific segments of DNA. Over time, PCR technology has evolved, giving rise to various methodologies, each tailored to specific needs. In this blog post, we will explore the different types of PCR and their applications.  Standard PCR Conventional PCR enables the

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What is NGS?

Leave a Comment / Oncology, Precision Medicine, Prenatal Testing, Product Application / By

Next-Generation Sequencing (NGS) is a cutting-edge technology used to sequence nucleotides in a DNA or RNA molecule. Unlike Sanger Sequencing, which can sequence only one DNA fragment at a time, NGS allows researchers to sequence multiple DNA fragments in parallel in a single run. This high-throughput approach revolutionizes our ability to decode complex genomes efficiently

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Mag-Bind® Environmental DNA 96 Kit: High Quality Extractions from Inhibitor-rich Samples

Leave a Comment / Agriculture, Environmental, Product Application / By

The characterization of the metagenomics of an ecosystem is an integral part of environmental research and understanding the role microorganisms play within their ecosystem. However, isolating high-quality DNA to allow for this characterization can be a challenge when it is being extracted from samples rich in inhibitors, such as humic and fulvic acid. The Mag-Bind®

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Mag-Bind® FFPE DNA Kit: The Ultimate Solution for Genomic DNA Purification from Formalin-Fixed Paraffin-Embedded Tissue Samples

Oncology, Product Application / By

Formalin-fixed paraffin-embedded (FFPE) tissue samples are commonly used for preserving and storing biological samples, such as cancer tumor samples, for future analysis. However, the formalin fixation and paraffin embedding process can significantly impact the quality and yield of extracted DNA, making it challenging for downstream applications such as PCR and NGS. Omega Bio-tek developed the Mag-Bind® FFPE

Mag-Bind® FFPE DNA Kit: The Ultimate Solution for Genomic DNA Purification from Formalin-Fixed Paraffin-Embedded Tissue Samples Read More »

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