DNA from Saliva Performs Well Downstream, Despite Poor A260/A230 Ratios

The non-invasive nature of sample collection makes saliva an appealing sample type for patients and researchers alike. However, one hindrance to using saliva for genomic analysis is the appearance of low purity in eluates when quantified using absorbance ratios. Here, we discuss the nature of absorbance ratios and contextualize their meaning when analyzing extractions from […]

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A Guide to Magnetic Bead-Based Nucleic Acid Extraction

Among the myriad techniques for nucleic acid extraction, magnetic beads stand out as an efficient and reliable tool to implement when automating extraction workflows. Magnetic bead-based extraction relies on the use of paramagnetic particles with coatings capable of specifically binding to nucleic acids. These beads only display magnetic properties when an external magnetic field is

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The Challenges of cfDNA Purification

Cell-free DNA (cfDNA) has emerged as a revolutionary tool in the realm of molecular diagnostics, offering a non-invasive window into the genetic information of various bodily tissues. As discussed in a previous post, the development of cfDNA technology is a large step forward in detecting and profiling circulating biomarkers to derive clinically relevant information. However,

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Webinar December 14th

Omega Bio-tek invites you to join us for a live event on December 14th at 10:00 a.m. ET where we will introduce the new standard for high-volume, cost-effective nucleic acid purification. In this event, you will hear from some of our experts, Brandon Easparro, Chris Stuart, and Tesfaye Kemsi, about the MagBinder® Fit24, your ultimate

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The future of high-volume, cost effective nucleic acid purification…

The future of Nucleic Acid Purification will be revealed… December 14, 2023 Introducing the MagBinder® Fit24 – the New Standard for High-Volume, Cost-Effective DNA/RNA Extraction Omega Bio-tek, an innovator of nucleic acid purification applications for 25 years, announces the release of the MagBinder® Fit24, its first piece of hardware for labs isolating DNA or RNA

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DNA Sequencing Could Help Restore Genomic Diversity to at-risk Populations of Pumas in California

Introduction The consequences of the expansion of human development have been especially felt in California where human activity has eradicated several apex predators, like the California Grizzly and gray wolf. Unlike these predators, the puma, also called the mountain lion or cougar, has continued to populate the state, though their population is threatened by the continued

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What is PCR?

Polymerase Chain Reaction (PCR) is a molecular biology technique used to amplify and replicate specific segments of DNA. Over time, PCR technology has evolved, giving rise to various methodologies, each tailored to specific needs. In this blog post, we will explore the different types of PCR and their applications.  Standard PCR Conventional PCR enables the

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What is NGS?

Next-Generation Sequencing (NGS) is a cutting-edge technology used to sequence nucleotides in a DNA or RNA molecule. Unlike Sanger Sequencing, which can sequence only one DNA fragment at a time, NGS allows researchers to sequence multiple DNA fragments in parallel in a single run. This high-throughput approach revolutionizes our ability to decode complex genomes efficiently

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